July 7, 2011
Study: Resveratrol Mimics Benefits Of ExerciseTopics: Health Issues
A new study, published June 30 in the Federation of American Societies for Experimental Biology Journal, seems to provide a reason for the longstanding French paradox that despite a diet high in rich foods like cheese and cream, the French enjoy a low death rate from heart disease. According to the study, the star ingredient in wine, resveratrol, could slow the negative consequences of a sedentary lifestyle like insulin resistance and loss of bone mineral density.
From The Independent:
[...] The study, published June 30 in the Federation of American Societies for Experimental Biology Journal, claims that the star ingredient in wine, resveratrol, could slow the negative consequences of a sedentary lifestyle like insulin resistance and loss of bone mineral density.Although the FASEB Abstract linked to in the article doesn't provide any indication of the dosage given to the rats in the study, the article does refer to 2008 lab study out of Germany in which researchers found that resveratrol inhibited pre-fat cells in humans from increasing and converting into mature fat cells, and also hindered the storage of fat:
[...] While the control group showed a decrease in muscle mass and strength, developed insulin resistance and a loss of bone mineral density, the group that received a dose of resveratrol showed none of the complications, the study said.
[...] They also found that resveratrol reduced the production of certain cytokines - cell-signaling protein molecules - that may be linked to the development of obesity-related disorders like diabetes and clogged coronary arteries.As the article goes on to note, one glass of red wine contains about 1 mg of resveratrol, and supplements contain 15 to 500 mg per capsule. Currently, there is no consensus on the safe and effective daily dosage of resveratrol, but supplementation should be avoided by pregnant or breastfeeding women.
Read the whole thing here.
Recommendation: For those interested in taking a resveratrol supplement, be aware that published research suggests that only the trans- form (100 mg/day is ample) has considerable biological activity.
Posted by Richard at July 7, 2011 10:30 AM
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