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May 2, 2007

Coffee Can Protect Against Type 2 Diabetes And Cancer

Topics: Health Issues

cafe_coffee2.jpgCoffee contains hundreds of components including substantial amounts of chlorogenic acid, caffeine, magnesium, potassium, vitamin B3, trigonelline, and lignans. Limited evidence suggests that coffee may improve glucose metabolism by reducing the rate of intestinal glucose absorption and by stimulating the secretion of the gut hormone glucagon-like peptide-1 (GLP-1) that is beneficial for the secretion of insulin. With these details in mind perhaps, attendees at the American Society for Nutrition's popular "controversy session" at Experimental Biology 2007 have said that drinking coffee can help ward off type 2 diabetes and may even help prevent certain cancers. Interestingly, coffee components other than caffeine may be beneficial for glucose metabolism:

"We`re coming from a situation where coffee had a very negative health image," Dr. Rob van Dam of the Harvard School of Public Health, who has conducted studies on coffee consumption and diabetes, told news agencies. Nevertheless, he added, "it`s not like we`re promoting coffee as the new health food and asking people who don`t like coffee to drink coffee for their health."

Van Dam participated in a "controversy session" on coffee at the Experimental Biology 2007 meeting underway in Washington, D.C.

Dr Lenore Arab of the David Geffen School of Medicine at UCLA also took part, presenting results of a review of nearly 400 studies investigating coffee consumption and cancer risk.

There`s evidence, Arab noted, that the beverage may protect against certain types of colon cancer, as well as rectal and liver cancer, possibly by reducing the amount of cholesterol, bile acid and natural sterol secretion in the colon, speeding up the passage of stool through the colon (and thus cutting exposure of the lining of the intestine to potential carcinogens in food), and via other mechanisms as well.

However, Arab did find evidence that coffee may increase the risk of leukemia and stomach cancer, with the case for leukemia being strongest.

The findings suggest that people who may be vulnerable to these risks -- for example pregnant women and children -- should limit coffee consumption, van Dam noted in an interview.

He and his colleagues are now conducting a clinical trial to get a clearer picture of the diabetes-preventing effects of coffee, which were first reported in 2002. Since then, he noted, there have been more than 20 studies on the topic.

Van Dam and his team are also looking for which of the "hundreds to thousands" of components of coffee might be responsible for these effects. It`s probably not caffeine, he noted, given that decaf and caffeinated coffee have similar effects on reducing diabetes risk.

His top candidate, van Dam says, is chlorogenic acid, an antioxidant that slows the absorption of glucose in the intestines.

More here ...

Posted by Richard at May 2, 2007 9:57 AM



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