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April 5, 2006

Cox2 inhibitors play a role in fighting some cancers?

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The results of a recent study suggests that women who have been taking the anti-inflammatory Cox-2 inhibitors such as Celebrex for a period of more than 2 years, have a possible less risk of developing breast cancer.

The researchers studied the breast tissue of women who had developed hyperplasia and they discovered that the women with high levels of cox-2 went on to develop breast cancer. A similar study relating to colon cancer has discovered that people who take Cox-2 inhibitors are less likely to develop colon cancer.

These results contain good news and bad news, because the minimum dose of the Cox-2 inhibitors required to protect against these cancers is an unknown quantity. At the present time there is only one drug available on the open market that is being sold as a Cox-2 inhibitor - Celebrex. On the negative side is the potential for this drug to produce unwanted side effects such as hypertension as well as the possibility of causing a heart attack. (NOTE - if the person already has heart problems then that person should either not be given Celebrex or must be monitored very closesly). At this point in time there is no definite research that shows how the benefits outweigh the risks.

Perhaps the answer might lie in researching natural herbal alternatives to the manufactured Cox-2 inhibitors.

Posted by at April 5, 2006 2:59 AM



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