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March 2, 2006
Study Says Tequin Could Produce Diabetes
Topics: Medicine
A Canadian study urges doctors to stop prescribing the Bristol Myers Squibb antibiotic, Tequin (gatifloxacin), saying it can have "life threatening" side effects, including diabetes.
Elderly people who took the medication were 17 times more likely to develop serious diabetes than if they took a different antibiotic, and were four times more likely to be hospitalized for low blood sugar.
The study was slated for a March 30 publication date in The New England Journal of Medicine, but was released earlier due to the importance of its findings.
A research Study using rats indicates that Gatifloxacin-induced secretion of insulin and epinephrine would contribute to the abnormalities in glucose homeostasis (see link below).
Related: Effects of gatifloxacin on serum glucose concentration in normal and diabetic rats.
Cross posted to Diabetologica
Posted by Richard at March 2, 2006 4:50 PM
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