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October 7, 2005

Hormonal Therapy Added to Radiation Improves Prostate Cancer Outlook

Topics: Medicine

An Australian and New Zealand study suggests that three months of testosterone suppression therapy before and during radiotherapy for locally advanced prostate cancer improves over radiation treatment alone, and six months is even better.

Patients who had three months of androgen deprivation starting two months before radiotherapy for control of prostate cancer had almost half the risk of local failure as patients who received radiation alone.

Doubling the duration of hormonal therapy to six months cut the risk that patients would die from prostate cancer by almost half.

Although three months' testosterone suppression reduced the risk of cancer returning in the prostate itself, it did not reduce the risk of metastasis or increase cancer survival.

Following the study, physicians are advised to advise their patients that this study indicates that androgen deprivation therapy administered for five months before and one month during radiotherapy for locally advanced adenocarcinoma of the prostate is associated with significantly better control of disease and longer cancer-free survival than radiotherapy alone.

Posted by Richard at October 7, 2005 1:22 AM

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