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September 20, 2005

Skin Patch Eases Early and Late Parkinson's Symptoms

Topics: Medicine

An investigational skin patch (not FDA-approved) delivering the dopamine receptor agonist rotigotine for Parkinson's disease, has been shown to be effective at relieving symptoms and improving functioning in patients with both early and late-stage disease.

According to the drug's manufacturer, after 24 to 48 hours of continuous use of the patch, blood plasma levels of rotigotine stabilize and remain steady over the 24 hours that the patch is meant to be worn. The drug is reported to have good bioavailability because it is not subjected to first-pass hepatic metabolism. No drug-drug interactions with levodopa, carbidopa, cimetidine or domperidone have been observed, according to Schwarz Pharma AG in Manheim, Germany.

It's important to know that the data and conclusions were reported in abstracts and presented orally at a conference, and therefore should be considered to be preliminary, as they haven't yet been reviewed and published in a peer-reviewed publication.

Tags: Parkinson's Disease

Posted by Richard at September 20, 2005 7:39 AM

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