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April 22, 2005

Diabetes Drug May Be Effective Against Some Cancers

Topics: Medicine

A drug commonly used to treat Type 2 diabetes may prevent cancer, researchers have said.

The team studied cancer rates among 6,000 people with diabetes and found those who took metformin cut their risk of all tumour types by more than 25%.

A larger study to verify the University of Dundee team's findings, published online at, will begin soon.

Ultimately, metformin might be used as an anti-cancer drug, the researchers said at Diabetes UK's annual meeting.

They found the metformin group had far fewer cancers than the other group - in the order of 20-40%.

They believe that the drug protects against cancer by switching on an enzyme in the body called AMPK.

This enzyme tricks cancer cells into thinking that they have insufficient sources of energy to grow.

More at BBC News ...

Related - Could diabetes treatments fight cancer?

Posted by Hyscience at April 22, 2005 10:55 AM

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