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March 22, 2005

Compound Blocks Known Cancer-Causing Protein

Topics: Clinical Pharmacology

Comprehensive Cancer Center scientists have discovered a potential new drug that inhibits destructive cell signals that drive the growth of one-third of all cancers. The scientists showed they could block the growth of cultured colon cancer cells using this new compound, called cysmethynil.

Their finding, reported in the March 22, 2005, issue of Proceedings of the National Academy of Sciences, is the first step toward developing a new class of anti-cancer drugs that block the Icmt protein from activating uncontrolled cell growth, a hallmark of cancer, according to Patrick Casey, Ph.D. Casey is the study's senior investigator and Duke pharmacologist and cancer biologist.

(...) "This is the first selective small molecule inhibitor of Icmt, a protein that has been shown to be an important player in keeping a cancer-causing gene called 'Ras' turned on inside cells,"

Hat tip - Science Blog

Posted by Hyscience at March 22, 2005 12:34 PM

Thank you for steering us to that wonderful posting from Australia. It may be more than coincidence that this event so resembles a passion play at this particular time of the year...

I am posting the following at several sites - just an idea of something to do:

This morning I awoke, exhausted still, not resting enough as I pray for Terri. I phoned the Florida State Senator offices requesting they change their vote on the bill for Terri's life, and faxed a message to President Bush, requesting that he take Terri into protective custody if he could and thanking him for his heart and all that he has done to try to help and save her life. I thought about if there was anything else that I could do.

I thought of one more thing:
I phoned the US Court of Appeals, 11th Circuit in Atlanta at (404) 335-6100, and simply requested to leave a message for the Hon. J.L. Edmonson, the Chief Judge of the court. The woman at the other end was polite, courteous, even kind and asked me what message I would like her to relay. I just said that I would ask the Hon. Edmonson to please allow Terri's feeding tube to be restored, while the appeals court considers the entire case concerning Terri. The woman I spoke with said thank you, and that she would pass my message on.

I thought that perhaps all of us might call and leave a similar message for the appeals court.

Thanks.

Posted by: Julie at March 22, 2005 2:24 PM



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