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February 18, 2005

Heart disease painkiller warning

Topics: Health Issues

Cox-2 inhibitors are still in the limelight for having problems, while work is underway to better understand COX-3 and the mechanism of action of paracetamol/acetaminophen.

European regulators have said patients who have had heart disease or a stroke should not take a common painkiller.

The European Medicines Agency said doctors should also be "cautious" about giving Cox-2 inhibitors to patients who have risk factors for heart disease.

These can include high blood pressure, high cholesterol and smoking.

Patients in these groups who are already taking Cox-2s are do not need to stop taking them, but should discuss their treatment with their GP.

The news comes as the US Food and Drug Administration carries out its own investigation into the safety of Cox-2s.

Posted by Hyscience at February 18, 2005 7:03 AM

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