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January 11, 2005

Progress toward gene therapy in AIDS: Researchers find monkey gene linked to blocking AIDS

Topics: Medicine

Studying differences in the gene products of the monkey and human Trim 5 alpha genes, researchers were able to pinpoint one specific change in a protein that was important in blocking HIV. They substituted a human protein with a monkey-derived protein and found that they could make the human cells resistant to HIV - and that is a significant development toward developing effective gene therapy to combat AIDS.

ABCNEWSonline (Australia) Jan 11
A single change in a human gene may hold the key to preventing people living with HIV from progressing to full-blown AIDS, researchers say.

They found a crucial difference between a gene in humans and one in rhesus monkeys that blocks infection of the virus in the animals - a finding that offers new insights into the origins of AIDS and gene therapy.

Had the gene been the same in humans, scientists at the National Institute of Medical Research in London believe, there may not have been the AIDS epidemic that now affects 40 million people worldwide.        Read more...

Posted by Hyscience at January 11, 2005 1:24 PM

i need ful details about gene therapy in aids.

Posted by: balaji at January 26, 2005 2:55 AM



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